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CardioBreak: Statins and Sex, Tekturna Black Box

— Recent developments of interest in cardiovascular medicine.

MedpageToday

Are statins a plus or minus for ? The New York Times digs in.

Percutaneous compared with intra-aortic balloon pumps in high-risk PCI and cardiogenic shock, researchers found.

Nearly half of interventional cardiologists reported in a survey by the Society for Cardiovascular Angiography and Interventions.

The FDA rejected a petition from watchdog group Public Citizen aiming at a black box warning on ACE inhibitors, angiotensin receptor blockers (ARBs), and aliskiren (Tekturna) regarding risk of hypotension, high potassium levels, and kidney failure when combining two or more of these. It did agree to a with either ACE or ARB in diabetes patients.

European regulators issued guidance on studies into treatment of venous thromboembolism, which for the first time set .

Rivaroxaban (Xarelto) was associated with fewer hospital admissions and lower costs compared with standard treatment for deep vein thrombosis, an observational study out of the Hospital Medicine congress showed. Janssen trumpeted the findings .

Atrial fibrillation patients most likely to over- or underestimate their arrhythmia symptoms: those with persistent afib, women, older adults, and those diagnosed with anxiety or depression. See the study .

The real-world use registry is now open for the in symptomatic afib, Medtronic announced.

CardiAQ Valve Technologies got clearance for a small feasibility study for a for severe symptomatic mitral regurgitation in high-surgical risk patients.

The peripheral EverFlex stent maintained "acceptable" patency with a less than 1% fracture rate over 3 years in long, complex, superficial femoral and popliteal arteries in the single-arm .

The lab company accused of kickbacks and illegal sales, marketing, and billing around has settled with the Department of Justice, although criminal charges are still on the table for company executives, CardioBrief's Larry Husten reports. More juicy financial details are coming this week.

"Legendary" Baltimore cardiologist , past president of the Association of Black Cardiologists and the International Society of Hypertension in Blacks, died April 6.

The AdaptivCRT algorithm by 46% compared with device settings optimized conventionally by echocardiography in heart failure patients, analysis of a trial showed.

The most effective way to get heart failure patients to might center on changing patient behaviors, a meta-analysis found.

The National Lipid Association issued its final report on , which emphasize monitoring LDL and having a hard target. See here for MedPage Today's coverage of the earlier draft.

Surprise: physically-active middle age people are unlikely to .

CardioBreak is a guide to what's new and interesting on the Web for cardiologists and other healthcare professionals with an interest in cardiovascular disease, powered by the MedPage Today community. Got a tip? Send it to us: c.phend@medpagetoday.com.