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Recalled Pacemakers; FDA Rejects Full Andexxa Approval; Ticagrelor Back in Hot Seat

— Recent developments of interest in cardiovascular medicine

MedpageToday
Cardio Break over a computer rendering of a heart.

The FDA is alerting clinicians to a recall of , which have an increased risk of permanently entering "safety mode," possibly requiring early device replacement.

The agency also cleared the designed for more precise, clinically meaningful BP and pulse rate measurements, manufacturer Withings Health Solutions said.

In addition, the FDA for andexanet alfa (Andexxa) a month after an advisory committee highlighted uncertainties about which dose and in which patients it could best be used. (Endpoints News)

NFL player Damar Hamlin of the Buffalo Bills expressed excitement over the likely passage of the , which would ensure lifesaving care in schools. (WTAE)

A BMJ investigation resurfaced old doubts about the while raising new questions about the possibility of unblinding in the study.

Researchers identified a way to deliver in a mouse model of pre-eclampsia. (Nature)

did not bode well for cognition in older adults in a prospective observational cohort study. (Neurology)

It is possible to have over time, according to serial measurements from patients in the OCEAN(a)-DOSE trial. (Journal of the American College of Cardiology)

The seems to play a role in the progression of atherosclerosis, and may be helped by a good diet, results from the CORDIOPREV study showed. (European Heart Journal)

A quality improvement intervention in patients with ischemic stroke for endovascular thrombectomy, a cluster randomized trial found. (JAMA Neurology)

A judge ruled that lawyers for former Minneapolis police officer Derek Chauvin can get tests done on preserved samples of after a pathologist hypothesized that high catecholamines or Takotsubo myocarditis may have caused Floyd's death. (CBS News)

Tricuspid valve surgery was associated with improved survival for , according to an observational analysis. (Heart)

The American College of Cardiology highlighted observational research suggesting that was associated with an increased risk of premature cardiac injury.

Results of a secondary analysis of the randomized REPRIEVE trial showed a potential mechanism for how statins benefit people with HIV through . (JAMA Cardiology)

was linked to an increased risk of venous thromboembolism in the prospective Multi-Ethnic Study of Atherosclerosis cohort. (Blood)

An estimated 15 million adults in the U.S. have a , according to a cross-sectional study using PREVENT equations. (Annals of Internal Medicine)

Short-term concomitant use of the muscle relaxant dantrolene may be protective against , in vivo and in vitro experiments suggested. (JACC: CardioOncology)

Sensome announced results from two studies showing that their can identify clots rich in red blood cells to support decision making in the treatment of peripheral artery disease.

An individual-level meta-analysis supported a benefit with . (The Lancet)

  • author['full_name']

    Nicole Lou is a reporter for MedPage Today, where she covers cardiology news and other developments in medicine.