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One-Year CGM Cleared; Osteoporosis Lawsuits Revived; Chemicals and Early Puberty

— News and commentary from the endocrinology world

MedpageToday
Endo Break over a computer rendering of a man with illustrated body organs.

The FDA as the first 1-year integrated continuous glucose monitoring (CGM) system for adults with type 1 or type 2 diabetes, said maker Senseonics.

Habitual -- 200-300 mg of caffeine/day -- was tied to a lower risk of cardiometabolic multimorbidity, a U.K. Biobank analysis found. (Journal of Clinical Endocrinology & Metabolism)

A U.S. appeals court alleging Merck failed to warn patients about an increased risk of thigh bone fractures with alendronic acid (Fosamax) for osteoporosis. (Reuters)

In chronic kidney disease (CKD) patients with diabetes and obesity, metabolic surgery was tied to a 60% lower risk of and a 44% lower risk of kidney failure or death compared with GLP-1 receptor agonist use, an observational study found. (Annals of Surgery)

HbA1c among young people with type 1 diabetes was 2.5 percentage points lower after 13 weeks with the MiniMed 780G compared with usual care in a small open-label trial. (NEJM Evidence)

One performed between 24 to 28 weeks gestation missed 72% of gestational diabetes cases in a Japanese study. (Journal of Diabetes Investigation)

Sen. Bernie Sanders (I-Vt.) said the would expand coverage of diabetes and weight-loss injectable semaglutide (Ozempic, Wegovy) if maker Novo Nordisk lowered its list prices. A 1-month supply in the U.S. ranges from $935 to $1,350 depending on the indication. (Reuters)

Linked to the growing use of biologics in recent years, the among rheumatoid arthritis patients at one German center dropped from 49% in 1996-2004 to 28% in 2005-2019, with corresponding decreases in fractures as well. (RMD Open)

-- including substances used in detergents, perfumes, and personal care products -- may trigger early puberty in girls, research in Endocrinology suggested. "The ability of these compounds to stimulate key receptors in the hypothalamus -- the gonadotropin-releasing hormone receptor and the kisspeptin receptor -- raises the possibility that exposure may prematurely activate the reproductive axis in children," study author Natalie Shaw, MD, MMSc, of the National Institutes of Health, said in a statement.

The FDA cleared See-Mode Technologies' and reporting software.

Obesity or overweight in childhood was linked with a later in life. (Science Advances)

Compared with other medications for type 2 diabetes, patients had a 179% greater likelihood of developing non-arteritic anterior ischemic optic neuropathy, a vision-threatening condition, data from Epic Research found.

  • author['full_name']

    Kristen Monaco is a senior staff writer, focusing on endocrinology, psychiatry, and nephrology news. Based out of the New York City office, she’s worked at the company since 2015.