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Gastroenterology

News, opinions and meeting coverage in gastroenterology.

A computer rendering of a transparent female body with a fatty liver highlighted.

Serious Outcomes of Steatotic Liver Disease Hit Men and Women Differently

Liver cancer risk higher among men, while cirrhosis more common in women

A computer rendering of a healthy colon.

Some Older Adults Think Stopping CRC Screening at Age 75 Is 'Unacceptable'

Limited life expectancy may not increase acceptance of such guidelines, researchers say

A photo of a wad of rolled up $100 bills in a prescription medication bottle.

Drug Prices Negotiated by Medicare Still Higher Than Other Countries'

All drugs except one remained more expensive in the U.S.

Benefits of HPV Vaccination; Contraindications to Newer Obesity Drugs

Also in TTHealthWatch: minimum effective dose of pneumococcal vaccines

Doctors performing colonic resection surgery.

Lidocaine Fails to Speed Up Gut Function Recovery After Colonic Surgery

Absence of gut function recovery is the primary reason for extended hospital stays

A computer rendering of monoclonal antibodies.

Mirikizumab Effective in Crohn's Disease After Initial Standard Therapy Failure

Study also showed the monoclonal antibody was noninferior to ustekinumab

Photo of a bottle of white pills.

U.K. Data Tie Acetaminophen to Increased Ulcer Risk

Not so stomach-safe after all?

Surgical instruments and supplies lay on a table during a kidney transplant surgery.

New Rule Allows HIV-Positive Organ Transplants

Previously, such transplants could be done only as part of research studies

Pouring whisky away down the sink.

Many Drinkers Cut Back After Starting Obesity Meds, Study Finds

In WeightWatchers study, 45% decreased their alcohol use after initiating a weight-loss drug

Image of the vegetable department of a grocery store.

Have Foodborne Illness Outbreaks Really Increased?

The answer may have more to do with how we track them, experts say

A photo of a cooked turkey.

Do Not Wash Your Turkey and Other Thanksgiving Tips to Keep Your Food Safe

Ways to avoid food-related danger during the holidays

2024 YEAR IN REVIEW IBD

Year in Review: Inflammatory Bowel Disease

"Top down" vs "step up" therapy, FDA actions, rethinking placebos, and new tulisokibart data

Crohn's Disease, Ulcerative Colitis Linked to Pesticide Exposure

Elevated risk of IBD for people exposed to environmental pollutants in the prior decade

FDA APPROVED zanidatamab (Ziihera) over a computer rendering of the gall bladder.

FDA Approves Zanidatamab for Biliary Tract Cancer

New antibody indicated for previously treated, unresectable or metastatic HER2-positive disease

AASLD over a photo of San Diego Convention Center in San Diego, CA.

Novel Therapy Reduced Liver Fat, Improved Fibrosis in MASH

Liver fat reductions were sustained for up to a year with the thyroid hormone receptor agonist

AASLD over a photo of San Diego Convention Center in San Diego, CA.

'A Watershed Moment': GLP-1 Drug Succeeds in Late-Stage MASH Trial

First positive phase III study for a GLP-1 agonist in chronic liver disease

AASLD over a photo of San Diego Convention Center in San Diego, CA.

Tapered Steroid Dosing Safe, Effective in Severe Alcohol-Associated Hepatitis

Notably, tapering reduced the risk of infection compared with a fixed dose

AASLD over a photo of San Diego Convention Center in San Diego, CA.

New MELD Model Improves Access to Liver Transplant for Women

A greater proportion of women on the waitlist and undergoing transplant since adoption

AASLD over a photo of San Diego Convention Center in San Diego, CA.

Immunotherapy Shows Promise in Downstaging Liver Tumors Prior to Transplant

78% of patients in prospective study had tumor downstaging with immune checkpoint inhibitors

ACR over a photo of Walter E. Washington Convention Center in Washington, D.C.

Study: Statins Mitigate Heart Risks From JAK Inhibitors

Is this the final finding from ORAL Surveillance? Don't count on it.

AASLD over a photo of San Diego Convention Center in San Diego, CA.

Fecal Therapy Shows Survival Benefit in Severe Alcoholic Hepatitis

Improved markers of disease severity as well in small trial of steroid-ineligible patients

A photo of surgeons performing a liver transplant.

Alarming Surge in Alcohol-Related Liver Transplants in Younger Adults

Targeted preventive strategies needed, especially for younger women, researchers say

A photo of a man holding a semaglutide injection pen.

GLP-1 Drugs Could Help People With Alcohol Use Disorder

Real-world data suggested semaglutide, liraglutide reduced AUD-related hospitalizations

A photo of bottles of Ocaliva tablets over a computer rendering of the gallbladder with bile duct and biliary tree.

FDA Rejects Full Approval of Liver Disease Drug

Agency's decision on obeticholic acid in PBC follows negative advisory committee meeting

ACG over a photo of Pennsylvania Convention Center in Philadelphia, PA.

Do GLP-1 Agonists Really Need to Be Stopped Before Endoscopy?

Meta-analysis suggests 24-hour clear liquid diet works to avoid aspiration, even with GLP-1s

ACG over a photo of Pennsylvania Convention Center in Philadelphia, PA.

ACG Roundup: Young-Onset Barrett's Esophagus on the Rise

Selected highlights from the 2024 American College of Gastroenterology annual meeting

ACG over a photo of Pennsylvania Convention Center in Philadelphia, PA.

Rifaximin Reduced Overt Hepatic Encephalopathy Recurrence Over Lactulose

Rifaximin also reduced mortality, but its high cost may be a barrier

ACG over a photo of Pennsylvania Convention Center in Philadelphia, PA.

AI Colonoscopies: More Benign Lesion Removals, Potentially Higher Costs

At scale, the benefits of AI-assisted colonoscopy may not always outweigh the costs

ACG over a photo of Pennsylvania Convention Center in Philadelphia, PA.

Novel Drug Improved Symptoms in Eosinophilic Esophagitis

Monoclonal antibody cendakimab also reduced eosinophils compared with placebo

A selfie of Brittany Randall and her daughter Kamberlyn Bowler in Grand Junction Colorado in the summer of 2024.

Colorado Teen Fights Kidney Failure After Eating McDonald's Quarter Pounders

Deadly E. coli outbreak has been tentatively traced to contaminated onions

ACG over a photo of Pennsylvania Convention Center in Philadelphia, PA.

Low-Volume Bowel Prep Matches Standard for Inpatient Colonoscopy

Patients also found MoviPrep to be more tolerable and were more willing to repeat it

A computer rendering of bits of DNA in the blood stream.

Blood Test for CRC Screening Lags Behind Other Options in Cost-Effectiveness Study

Fewer cancers, cancer deaths prevented; higher cost per quality-year saved

A photo of a McDonald’s Quarter Pounder hamburger and fries.

At Least 75 People Sickened as Deadly McDonald's E. Coli Outbreak Expands

Nearly two dozen people have been hospitalized

A computer rendering of a transparent body with a diseased liver highlighted.

Algorithm May Be Able to Predict HCC Risk in Advanced Chronic Liver Disease

Easy to apply, uses parameters commonly measured in outpatient and inpatient settings

YouTube thumbnail with Siobhan Deshauer, MD, holding a red pepper and the words: SPICY SCIENCE.

Are Spicy Foods Dangerous to Your Organs?

Spicy foods may have health benefits, but they also carry some risk

IDWeek over a photo of the Los Angeles Convention Center in Los Angeles, CA.

Are Norovirus Vaccines on the Horizon?

Two candidates leverage unique technologies

A Look at Food-Related Illnesses at Restaurants Over the Years

While pretty rare for well-known restaurant chains, they do happen

A photo of a fecal immunochemical test lying on a plastic envelope.

How Do Younger People Fare With Stool Tests for CRC Screening?

Retrospective study answers questions raised in shift to screening at age 45

Rainfall and Mortality; Identifying Risk for Preeclampsia

Also in TTHealthWatch: HIV-positive kidney donors

FDA APPROVED FDA has approved zolbetuximab (Vyloy) over a computer rendering of a monoclonal antibody and cancer cells.

Novel Targeted Drug Approved for Stomach Cancers

Zolbetuximab indicated alongside fluoropyrimidine- and platinum-containing chemotherapy

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