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Parkinson's Disease

News, opinions and meeting coverage in geriatrics.

A computer rendering of a neuron containing Lewy bodies.

In Parkinson's Disease, Cognitive Symptoms Often Emerge Soon After Diagnosis

About a third of patients reported a cognitive complaint in the first few years

A photo of three needles stuck into an acupuncture point model.

Sleep Quality Improved With Acupuncture for Parkinson's Patients

Benefits persisted at 8 weeks

Morning Break over illustration of a syringe, Covid virus, and DNA helix over a photo of green vegetation.

Researchers' Sexual Misconduct; 'Parkinson's on Steroids'; Need Surgery? Pay Upfront

Health news and commentary gathered by MedPage Today staff

Morning Break over illustration of a syringe, Covid virus, and DNA helix over a photo of green vegetation.

NYC Doc Arrested in Protest; Ozzy Osbourne's Stem Cell Tx; Metformin and COVID

Health news and commentary gathered by MedPage Today staff

Paxlovid and COVID; Breast Cancer and Lymph Node Removal

Also in TTHealthWatch: pragmatic model for chronic kidney disease

A computer rendering of nerve cells affected by Lewy bodies

Diabetes Drug Shows Benefit in Parkinson's Disease

Phase II study of GLP-1 drug lixisenatide meets primary endpoint

Aspirin for Fatty Liver; Meds for Self-Managed Abortion

Also in TTHealthWatch: diagnosing Parkinson's with a skin biopsy

A computer rendering of neurons containing Lewy bodies.

Skin Test Detects Parkinson's and Other Synucleinopathies

Cutaneous alpha-synuclein deposits may serve as a biomarker

A photo of a crop duster flying over a farm field in Oklahoma

Parkinson's Risk Tied to More Pesticides

Simazine, atrazine, lindane in the Rocky Mountain and Great Plains region emerge in new analysis

A computer rendering of neurons containing Lewy bodies

New Parkinson's Definition Proposed Based on Biomarkers

Framework focuses on the biology of Lewy body diseases

A computer rendering of nerve cells affected by Lewy bodies

Can a GLP-1 Agonist Improve Parkinson's Symptoms?

A version of exenatide failed a phase II trial, but hinted at benefits in patients under 60

A photo of a sad looking senior man sitting in a wheelchair outdoors.

Parkinson's Patients Have Higher Suicide Risk

About 1 in 5 harbored suicidal thoughts

A Parkinson’s patient walks with spinal stimulation. Credit: Courtine, et al.

Advanced Parkinson's Patient Regains Ability to Walk Confidently

Spinal implant nearly eliminates freezing of gait

A photo of a person using a stick welder.

Parkinsonism Case Tied to Welding, Improved With Chelation

How one team pinpointed manganese toxicity and diminished a patient's motor symptoms

A photo of a mature woman holding a cup of tea with both hands at home.

Loneliness Tied to Subsequent Parkinson's Risk

Findings support Surgeon General's recent call to improve social connection

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MedPod Today: Big Medical Bill; GLP-1 Agonist Plateau; Grateful Patient Fundraising

MedPage Today reporters offer further insights on these recently covered topics

A computer rendering of Lewy bodies inside a nerve cell.

Blood, CSF Marker Detects Parkinsonian Disorders

Enzyme also identified preclinical Lewy body disease

A photo of a marine rinsing his face off after tear gas training at Camp Lejeune Marine Corps Base

Parkinson's Linked With Industrial Solvents in Drinking Water

Exposure at age 20 led to 70% higher risk decades later, Camp Lejeune study shows

A photo of a man holding his trembling hand.

More Evidence Links Parkinson's With Autoimmune Disease

Exact mechanism remains speculative, however

AAN over a photo of the Boston Convention and Exhibition Center in Boston, MA.

No Pills, No Surgery, No Electrodes for Parkinson's Disease?

Minimally invasive devices to drip dopaminergic drugs edge closer to market

A photo of blue rubber gloved hands holding an assay plate.

Parkinson's Biomarker Shows High Accuracy

Assay identifies hallmark protein and could help diagnose people earlier

A photo of factories belching white smoke in a hazy sky

Nationwide Study Links Parkinson's Disease to Air Pollution

Researchers identify a hot spot in the Mississippi-Ohio River Valley

A graphical illustration of a focused ultrasound ablation of the brain.

Advanced Parkinson's Symptoms Improved With Focused Ultrasound

Pivotal trial shows 3-month improvement, but longer study is needed

A photo of a person holding a blisterpack of Epilium sodium valporate tablets.

Epilepsy Drugs May Up Risk of Parkinson's

Strongest association seen for sodium valproate

A diffusion tensor image of the corpus callosum, in a brain with Parkinson’s disease.

Parkinson's Incidence 50% Higher Than Previously Thought

Clusters of Parkinson's disease cases seen in certain U.S. regions

A photo of a box of deferiprone tablets over a computer rendering of a brain.

Brain Iron Chelation Linked With Worse Outcomes in Early Parkinson's

Findings raise caution about iron chelation in neurodegenerative disorders

A photo of a senior woman looking at her hands while pressing her ring fingers to her thumbs

Early Signs of Parkinson's May Be Seen Years Before Diagnosis

Skin changes, inflammatory conditions emerge, in addition to well-known features

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New Evidence Sheds Light on Muhammad Ali's Parkinson's Disease

Was boxing to blame?

A photo of a senior man holding his steadying his hand which is holding a spoonful of soup.

Cognitive Decline Quickens After Weight Loss in Early Parkinson's Disease

Early weight gain associated with cognitive changes, too

Nitin Sethi cutting a bandage off a boxer's hand following a fight.

The Internal Conflict of Being a Ringside Doctor

The aftermath of a 2019 fight nearly broke me

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Some 'Dopamine Bean' Supplements Show High Levels of Parkinson's Drug

Levodopa found in doses similar to those in prescription meds

A computer rendering of monoclonal antibodies.

Two Strikes and Monoclonal Antibodies Are Out for Early Parkinson's?

Failure of two agents in two phase II trials could spell the end for one avenue of treatment

A computer rendering of a sacral neuromodulation transmitter implanted.

Sacral Neuromodulation Promising in Neurogenic Lower Urinary Dysfunction

Refractory disease corrected, at least for the short term, in selected neurologic patients

AAN over a photo of the Washington State Convention Center, Seattle, WA.

Polypill Looks Good for Parkinson's

Fixed-dose product combining two standard drugs outperforms each alone in phase III

A portrait of a mature man cupping his ear with his hand in an effort to hear.

Hearing Loss, Epilepsy May Be Early Signs of Parkinson's Disease

Known symptoms like tremor spotted in primary care records 10 years before diagnosis

Strawberries, blueberries, grapes, red wine corks, and a bottle of balsamic vinegar

More Flavonoids, Better Parkinson's Outcome

Flavan-3-ols and anthocyanins consistently linked to lower mortality

A medical illustration of a dopaminergic neuron in parkinson’s disease.

Early Parkinson's Treatment: AAN Issues New Guidelines

Levodopa usually is best first therapy for motor symptoms, neurology group says

FDA APPROVED Exablate Neuro over a photo a man receiving treatment with this device.

Focused Ultrasound Approved for Advanced Parkinson's

Expanded indication includes medication-refractory PD patients with motor problems

A bottle of Nuplazid (pimavanserin) capsules over a photo of a senior woman hiding her eyes with her hands.

Parkinson's Drug Tied to Increased Hospitalizations, Death

Mortality risk persisted in people taking pimavanserin

A stressed looking senior woman next to a bottle of Nuplazid (pimavanserin) capsules.

Staying on Pimavanserin Cut Dementia-Related Psychosis Relapse

However, late-stage trial couldn't separate efficacy in dementia subtypes

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