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Alzheimer's Vaccines Are Back; Streamlining Prior Authorization; Rare APOE Variant

— News and commentary from the world of neurology and neuroscience

MedpageToday
Neuro Break over a computer rendering of neurons.

Interest in is back, according to interviews with 10 scientists and company executives. (Reuters)

Personalized using natalizumab (Tysabri) trough levels appeared feasible in relapsing-remitting multiple sclerosis in the first phase of the NEXT-MS trial. (Journal of Neurology, Neurosurgery, and Psychiatry)

Ubrogepant (Ubrelvy) halted migraine attacks better than placebo in a phase III trial. (The Lancet)

Neurologists offered suggestions to and improve care. (JAMA Neurology)

A higher glycemic index and glycemic load diet were linked with progression. (Annals of Neurology)

Food insecurity was linked with a , lower memory scores, and faster memory decline. (JAMA Network Open)

The rare APOE-R136S (Christchurch) variant APOE4-driven Alzheimer's pathologies in mouse and human neuron models. (Nature Neuroscience)

Intestinal inflammation was associated with age and in a cohort study. (Scientific Reports)

Sex differences in were linked with Alzheimer's disease. (Alzheimer's & Dementia)

Nanoplastics influenced Parkinson's disease-associated in mice. (Science Advances)

A brain-penetrant USP30 inhibitor in a Parkinson's disease mouse model. (Nature Communications)

The New York Times offered a close look at the lives of with autopsy evidence of chronic traumatic encephalopathy (CTE).

  • Judy George covers neurology and neuroscience news for MedPage Today, writing about brain aging, Alzheimer’s, dementia, MS, rare diseases, epilepsy, autism, headache, stroke, Parkinson’s, ALS, concussion, CTE, sleep, pain, and more.