鶹ýӰ

Brain Clock Disparities; How Morphine Relieves Pain; Tolebrutinib and MS Disability

— News and commentary from the world of neurology and neuroscience

MedpageToday
Neuro Break over a computer rendering of neurons.

Brain clocks captured the diversity and and dementia in 15 countries. (Nature Medicine)

The FBI released a redacted portion of a that was one of the first to suggest the mysterious ailments were the result of "social contagion." (New York Times)

Researchers mapped out how , identifying a select set of neurons that formed a "morphine ensemble." (Science)

Electroencephalographic resembled those seen in early stages of Alzheimer's and related dementia, a systematic review showed. (Alzheimer's and Dementia)

Early treatment of a first acute myelin oligodendrocyte glycoprotein antibody-associated disease attack of a relapsing disease course. (JAMA Neurology)

The investigational Bruton's tyrosine kinase inhibitor tolebrutinib met its primary endpoint of delaying disability progression onset in a phase III study of people with (MS), but failed to reduce relapses in studies of relapsing MS versus teriflunomide (Aubagio), Sanofi said.

To date, real-life studies have not shown that like the Guardian Cap reduced brain injuries in American football, CNN reported.

The associated with SGLT-2 inhibitors -- mainly dapagliflozin (Farxiga) and empagliflozin (Jardiance) -- was less than that with DPP-4 inhibitors in people with type 2 diabetes, according to Korean data. (The BMJ)

Cholinesterase inhibitors slowed cognitive decline over 5 years in people who had compared with both nonuse and memantine (Namenda), Swedish registry data showed. (Alzheimer's and Dementia)

A phase III trial showed that the orexin receptor antagonist suvorexant (Belsomra) in older adults at high risk for delirium after hospitalization. (JAMA Network Open)

  • Judy George covers neurology and neuroscience news for MedPage Today, writing about brain aging, Alzheimer’s, dementia, MS, rare diseases, epilepsy, autism, headache, stroke, Parkinson’s, ALS, concussion, CTE, sleep, pain, and more.