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News, opinions and meeting coverage in primary care.

AAOS over a photo of Moscone Center in San Francisco, CA

Could Weight-Loss Drug Improve Hip Replacement Outcomes?

Two studies, two conclusions

A photo of PDE5 inhibitor erectile dysfunction drugs

Erectile Dysfunction Drugs Tied to Less Alzheimer's Risk

Large U.K. study tracked health records of 270,000 men

A microscope image of uric acid crystals

Early Marker Found for Long-Term Gout Flare Potential

And the bad news: urate-lowering therapy seemed to make no difference

A computer rendering beta amyloid accumulating between neurons

Even With Alzheimer's Pathology, Healthy Lifestyles May Preserve Cognition

More data support the idea of "cognitive reserve"

A computer rendering of a diseased liver.

Undiagnosed Liver Disease May Be Common in Patients With Dementia

Hepatic encephalopathy could be contributing to cognitive symptoms, study suggested

A photo of the packaging and vial of Aduhelm.

Controversial Alzheimer's Drug Abandoned

Biogen will stop developing and selling aducanumab

A photo of a young male doctor sitting across the desk from his senior female patient.

Some 'Choosing Wisely' Recs Protect Older Folks From Low-Value Care

Study looked at how three recommendations changed primary care decisions

A photo of a frozen pizza in an electric oven.

Dietary Factors Tied to Osteoarthritis Pain

But radiographic parameters not affected, raising questions about the link

Cancer After Weight Loss; How Older Adults Use the Healthcare System

Also in TTHealthWatch: PFAS guidelines for clinicians

A computer rendering of neurons containing Lewy bodies

New Parkinson's Definition Proposed Based on Biomarkers

Framework focuses on the biology of Lewy body diseases

A photo of a female nurse hugging her senior female patient at they sit on her bed together.

A Reminder of the Value of Hospice

What it is, what it isn't

A photo of the box of and blisterpack of diazepam tablets lying on the prescribing information

Benzodiazepines Tied to Worse Outcomes in Progressive Supranuclear Palsy

Drugs are commonly prescribed to treat insomnia, anxiety in PSP

A photo of a senior man walking on the beach in Australia

Adults Who Cite Walking Difficulty Face Higher Fracture Risk

Australian study suggests walking ability can help identify candidates for more assessment

A photo of gabapentinoid capsules in the palm of a man’s hand.

Gabapentinoid Use Continues to Climb

Gabapentin still commonly prescribed off-label for chronic pain

A photo of a tube of blood labeled Alzheimer’s disease held in blue rubber gloved hands in front of MRI images of a brain.

Alzheimer's Blood Test Shows High Diagnostic Accuracy

Commercial ptau-217 assay reduced confirmatory testing by about 80%

A photo of the Prolia auto injector and packaging.

FDA Slaps Boxed Warning on Osteoporosis Drug

Denosumab can cause severe hypocalcemia in patients with advanced CKD, agency finds

A photo of a car buried in deep snow during a blizzard in Davis, West Virginia.

Lovely Winter, the Killer

It's miserable for the weak, the sick, and the poor

A computer rendered cutaway of a spine affected by osteoporosis

Calcium Levels Quickly Become Critical for Many Denosumab-Treated Women on Dialysis

New findings led to boxed warning on drug's labeling for advanced CKD patients

An x-ray of a patient with an implanted biventricular pacemaker

Lives Prolonged for Longtime CRT-D Users With Heart Failure

Survival benefit with cardiac resynchronization therapy durable out to 14 years

Morning Break over illustration of a syringe, Covid virus, and DNA helix over a photo of green vegetation.

Kate Middleton Hospitalized; Sen. Paul Urges Prison for Fauci; COVID Back in Class

Health news and commentary from around the Web gathered by MedPage Today staff

A photo of people walking through a snowy Times Square in NYC.

Blinded by the Light? Outdoor Illumination Tied to AMD

Korean study suggests a link

A photo of hands holding a Viagra pill and a glass of water.

Erectile Dysfunction Drugs Plus Nitrates Still a Losing Combination, Study Shows

Cardioprotective effect of PDE5 inhibitors did not pan out with anti-anginals in the picture

A photo of two faceless mannequins.

Face Blindness Is Not Always Permanent

Largest study to date looks at inability to recognize familiar faces

A photo of President Joe Biden walking down the stairs from Air Force One.

Is President Biden a Super-Ager?

Experts say "age is a number, not a quality" -- even for the president

A photo of a female physical therapist leading her male client through exercises three months after knee replacement surgery

Non-White Military Members With OA Get Stiffed for Knee Replacement

Wide racial disparities in a health system that boasts equal access for everyone

A composite image of an Amsler grid laying over a photo of a persons eye

Dementia Drugs Seen Lowering Risk for Macular Degeneration

But not by very much or very quickly, VA analysis finds

A computer rendering of a patient who is receiving focused ultrasound

Opening Blood-Brain Barrier to Deliver Alzheimer's Drug Shows Promise

Focused ultrasound helped aducanumab reduce amyloid-beta levels

A computer rendering of a nerve cell affected by Alzheimer’s disease

Novel Alzheimer's Trials Evaluate Senolytics, Semaglutide, CRISPR, and More

Looking ahead to 2024 and beyond: "There is so much more to be done"

A photo of a senior man struggling to get up after falling in front of his couch.

Trio of Eye Diseases Linked to Falls, Fractures in Older Adults

Patients with cataracts, AMD, or glaucoma had 25% to 38% higher adjusted risks vs controls

A photo of a mature woman at home working out with barbells in front of a laptop

This Program Helped Overweight RA Patients Shape Up

Metabolic markers, disease activity improved with remotely supervised lifestyle regimen

Morning Break over illustration of a syringe, Covid virus, and DNA helix over a photo of green vegetation.

Fatal Christmas Tree; A Whole Lot of Fraud; Chatbots Relieve Seniors' Loneliness

Health news and commentary from around the Web gathered by MedPage Today staff

A photo of a womans hand on a railing

Frailty Worsens Side Effects of Rheumatoid Arthritis Treatment

Claims data highlight a neglected factor in RA therapy outcomes

A computer rendering of nerve cells affected by Lewy bodies

Can a GLP-1 Agonist Improve Parkinson's Symptoms?

A version of exenatide failed a phase II trial, but hinted at benefits in patients under 60

Morning Break over illustration of a syringe, Covid virus, and DNA helix over a photo of green vegetation.

Trump's Cognitive Exam; CDC Issues 'Urgent' Vaccination Alert; Plan B Use Doubled

Health news and commentary from around the Web gathered by MedPage Today staff

A photo of a senior man holding a blisterpack of capsules.

Experts Highlight Drug Overdose Deaths Among Seniors During Senate Hearing

Early CDC data suggest the problem is worsening

A photo of a mature man lying in bed awake with his arm across his forehead.

Dementia-Sleep Link Has a New Twist

Research unravels relationship between irregular sleep and poor brain health

A computer rendering of RSV viruses in the lungs.

Moderna's mRNA RSV Vaccine Effective in Older Adults

Whether it provides lasting protection remains to be seen

An MRI image of the brain of a person with Creutzfeldt-Jakob disease

Prion Disease Rising in the U.S.

Incidence of Creutzfeldt-Jakob disease increased, especially among women

A photo of a test tube of blood labeled: Alzheimer’s disease, laying on a stainless tray.

Alzheimer's Blood Test Predicts Who Might Benefit Most From Anti-Amyloid Drugs

Novel two-cutoff approach may reduce need for confirmatory PET scans

A photo of a female nurse holding her senior patient’s hand.

Intensive Caring: Reminding Patients They Matter

How to care for those who no longer care about themselves

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