'More Is Not Better' in Two First-Line Trials for Biliary Tract Cancer No survival benefit with three-drug chemo regimen or clear PFS gain with anti-PD-L1/bevacizumab Jan 22, 2023
Epstein-Barr Virus Tracking After Liver Transplant May Cut Rare Complication Observational study provides suggestive evidence Jan 17, 2023
Direct-Acting Antivirals Linked to Improved Outcomes in Chronic Hepatitis C All-cause mortality rate significantly lower in treated versus untreated group Dec 13, 2022
Abstinence Tied to Lower Mortality in Alcoholic Cirrhosis With Portal Hypertension Benefit observed even in patients with high-risk portal hypertension Dec 08, 2022
Robotic Surgery Proves Its Mettle for Liver Cancer Fewer cases of liver failure, similar survival versus open liver resection in matched analysis Nov 23, 2022
Will Fresh Look at Obeticholic Acid Data in NASH Sway FDA? Latest REGENERATE analysis comes on heels of REVERSE flop Nov 11, 2022
Steroids and G-CSF Boost 90-Day Survival in Severe Alcoholic Hepatitis Plus: Normothermic machine perfusion for liver transplants and Noom Weight for NASH Nov 11, 2022
Novel Hepatitis B Drug Hints at Long-Term 'Functional Cure' for Some in Early Trial With 10% efficacy at 6 months post-treatment, a finite HBV treatment may be on the horizon Nov 10, 2022
Efruxifermin Led to NASH Resolution, Fibrosis Improvement in Mid-Stage Trial Both 50- and 28-mg doses improved fibrosis vs placebo, without worsening of NASH Nov 10, 2022
Maralixibat Takes Out the Itch of Rare Liver Disease Ileal bile acid transporter inhibitor could become second drug for PFIC Nov 09, 2022
Odevixibat Shows 'Encouraging Results' for Kids With Alagille Syndrome Significant improvements in itching, bile acid levels for rare, life-threatening liver disorder Nov 09, 2022
Acamprosate Appears Safe for People With AUD and Liver Disease Phase II data suggest drug is well-tolerated and can reduce cravings in this group of patients Nov 09, 2022
BP Control Beneficial for Liver Transplant Recipients Patients who kept their blood pressure under 140/90 mm Hg had better kidney function at 1 year Nov 07, 2022
Earlier Terlipressin May Be Better for HRS-AKI in Acute-on-Chronic Liver Failure More acute kidney injury reversals at 7 days and lower mortality with initiation at 12 hours Nov 07, 2022
Pandemic's Impact on Liver Disease in the Spotlight at Liver Meeting A roundup of news from the AASLD annual meeting Nov 04, 2022
New HRS Drug Cuts Need for Renal Replacement Tx After Liver Transplant Follow-up data from CONFIRM trial show terlipressin benefit in key subgroup Oct 25, 2022
New Standard-of-Care Therapy for Advanced Liver Cancer Stereotactic body radiotherapy plus sorafenib improves survival versus targeted drug alone Oct 24, 2022
FDA Approves New CTLA-4 Inhibitor for Cancer Treatment Tremelimumab (Imjudo), in combination with durvalumab, lands approval in advanced liver cancer Oct 24, 2022
Bariatric Surgery in NAFLD Tied to Lower Heart Disease Risk In a large cohort, surgery associated with 49% lower risk of CVD versus nonsurgical care Oct 07, 2022
Noninvasive Gastric Mapping; Best Foods for the Gut? Lab Score for Crohn's News and commentary from the world of gastroenterology and hepatology Sep 22, 2022
Obeticholic Acid Tied to Better Outcomes in Primary Biliary Cholangitis Study comparing randomized trial with two external cohorts showed fewer deaths, transplants Sep 22, 2022
FDA Finally OKs First Drug for Hepatorenal Syndrome Pivotal trial data showed terlipressin nearly doubled reversal of the condition Sep 15, 2022
Ryan Reynolds' Colonoscopy; NASH Drug Passes Phase II Test; New Drug Target in IBD? News and commentary from the world of gastroenterology and hepatology Sep 14, 2022
More GI Docs, Fewer Alcoholic Liver Disease Deaths Study suggests access might account for 40% of alcohol-associated liver disease deaths nationally Aug 08, 2022
Adding TACE to Lenvatinib Boosts Survival in Advanced Liver Cancer In China-based trial, overall survival in first-line improved by 6 months versus lenvatinib alone Aug 04, 2022
Rare Mutations Linked to Protection Against Liver Disease Carriers of CIDEB variants were at lower risk for liver disease of any cause, study shows Jul 27, 2022
Novel Antifibrotic Improved Fibrosis in Chronic Hepatitis B Phase II trial from China suggests benefit of add-on therapy Jul 15, 2022
Unexplained Acute Hepatitis in Children: More Evidence for Adenovirus 41 Two studies point to a suspiciously high prevalence Jul 13, 2022
Odevixibat Scratches the Itch of Kids' Rare Liver Disease Phase III trial showed reduced pruritus in progressive familial intrahepatic cholestasis Jul 08, 2022
Hep C Cure Aside, Some Patients Still Benefit From Liver Cancer Screening Hepatocellular carcinoma risk persisted after direct-acting antivirals Jun 30, 2022
EASL Roundup: Path to 'Cure' in Hep B? Low-Carb, High-Fat Diet for NAFLD With T2D Noteworthy research from the European Association for the Study of the Liver annual meeting Jun 29, 2022
'A New Hope' for Rare, Deadly Liver Disease Small fazirsiran trial sees fibrosis regressions for liver disease associated with AAT deficiency Jun 28, 2022
Mixed Bag for Semaglutide in NASH-Related Compensated Cirrhosis Randomized trial showed improvements in cardiometabolic markers, but not liver fibrosis Jun 27, 2022
Liver Cirrhosis Tied to Elevated Risk for Stroke 37% higher risk observed in large German study Jun 25, 2022
Bulevirtide's Effect Sustained in Difficult-to-Treat Hepatitis D Nearly half of patients at week 48 had virological and biochemical response Jun 25, 2022
Early Liver Disease Detection Linked to Subsequent Lifestyle Improvements Danish study shows fibrosis screening associated with improved diet, alcohol use, and exercise Jun 24, 2022
Liver Preserved for 3 Days With Machine Perfusion Successfully Transplanted Patient healthy and leading normal life at 1 year Jun 01, 2022
POSE 2.0 Linked to Improved Outcomes in NAFLD Patients With Obesity Steatosis resolved in 53% of patients who underwent this minimally invasive procedure May 24, 2022
Medication for Drinking Addiction May Thwart Liver Disease Alcohol-related liver disease 63% lower for those taking medical addiction therapy May 20, 2022
MELD Scoring for Liver Transplants in Need of Sex Adjustment, Study Says Researchers find "pervasive sex differences" in sodium-adjusted MELD scoring system May 18, 2022
