Maralixibat Takes Out the Itch of Rare Liver Disease Ileal bile acid transporter inhibitor could become second drug for PFIC Nov 09, 2022
Odevixibat Shows 'Encouraging Results' for Kids With Alagille Syndrome Significant improvements in itching, bile acid levels for rare, life-threatening liver disorder Nov 09, 2022
Acamprosate Appears Safe for People With AUD and Liver Disease Phase II data suggest drug is well-tolerated and can reduce cravings in this group of patients Nov 09, 2022
Tenofovir, Vaccine Combo Eliminates Mom-to-Child HBV Transmission 100% success rate even without the use of hepatitis B immunoglobulin Nov 07, 2022
BP Control Beneficial for Liver Transplant Recipients Patients who kept their blood pressure under 140/90 mm Hg had better kidney function at 1 year Nov 07, 2022
Earlier Terlipressin May Be Better for HRS-AKI in Acute-on-Chronic Liver Failure More acute kidney injury reversals at 7 days and lower mortality with initiation at 12 hours Nov 07, 2022
Lucky to Be Scoped My screening colonoscopy went really well, but how many people don't get the chance to have one? Nov 07, 2022
Low Carb Diet Boosts Weight Loss for Liver Transplant Recipients With Obesity LCD also positively impacted patients' metabophenotype Nov 06, 2022
Psilocybin for Depression; What's the Best Direct Oral Anticoagulant? Also in TTHealthWatch: hormone therapy to prevent chronic disease Nov 05, 2022 podcast
Pandemic's Impact on Liver Disease in the Spotlight at Liver Meeting A roundup of news from the AASLD annual meeting Nov 04, 2022
Continuing Ozanimod Prevented More Relapses in Ulcerative Colitis Disease control also maintained with temporary withdrawal, at least initially Oct 28, 2022
Oral Microbiome Therapy Tied to Low Recurrence of C. Diff ECOSPOR IV study found low recurrence regardless of the number of prior episodes Oct 27, 2022
Upadacitinib Maintenance Triples Clinical Remissions in Crohn's Disease U-ENDURE trial also hit co-primary endpoint for endoscopic response Oct 27, 2022
Two More IBD Drugs Cleared for Safety During Pregnancy Ustekinumab, vedolizumab not linked to greater risk of complications Oct 26, 2022
Guselkumab-Golimumab Combo Shows Promise for Ulcerative Colitis More clinical remissions, endoscopic improvements, early trial finds Oct 26, 2022
New HRS Drug Cuts Need for Renal Replacement Tx After Liver Transplant Follow-up data from CONFIRM trial show terlipressin benefit in key subgroup Oct 25, 2022
Adding Electric Stimulation Bests Pyloroplasty Alone for Gastroparesis Randomized trial showed improved symptoms at 3 months with gastric electrical stimulation Oct 25, 2022
Virtual Reality Improved Functional Dyspepsia Symptoms, Quality of Life Intervention "recalibrates the perception of pain in a very powerful manner," researcher explains Oct 24, 2022
New Standard-of-Care Therapy for Advanced Liver Cancer Stereotactic body radiotherapy plus sorafenib improves survival versus targeted drug alone Oct 24, 2022
Higher Upadacitinib Dose May Be Better for UC Maintenance Post-hoc analysis suggested less severe disease and longer remission over 1 year Oct 24, 2022
FDA Approves New CTLA-4 Inhibitor for Cancer Treatment Tremelimumab (Imjudo), in combination with durvalumab, lands approval in advanced liver cancer Oct 24, 2022
Extra Hep B Vaccine Dose Exceeds Expectations for People With HIV Seroprotection seen in 100% of participants after three doses of Heplisav-B vaccine Oct 23, 2022
Oral Microbiome Therapy for Recurrent C. Diff Mostly Holds Up at 6 Months Half as many patients receiving SER-109 experienced recurrences versus placebo group Oct 21, 2022
Does Rheumatoid Arthritis Get Its Start in the Gut? Patients and at-risk individuals show antibodies to common intestinal bacterium Oct 20, 2022
Do Crohn's Patients Do Better With Early Surgery? Danish study finds fewer reoperations, though higher risk for hospitalization Oct 20, 2022
Probiotics in the ICU Linked to Higher Risk of Central Line Infections, Death Powder formulations associated with highest risk of infection Oct 19, 2022
Eating More Unprocessed Foods Tied to Lower Risk of Crohn's Disease No association seen for ulcerative colitis, however Oct 14, 2022
U.S. Experts Weigh In on Colonoscopy Status in Wake of European Trial Concerns abound after study suggests colonoscopy may be less effective than expected Oct 12, 2022
Vonoprazan Just as Good or Better Than Lansoprazole for Erosive Esophagitis Randomized trial shows noninferiority for healing and superiority for maintaining healing Oct 12, 2022
If You Invite 455 People to Colonoscopy, You'll Stop One Case of Cancer Risk of colorectal cancer reduced with screening in randomized trial, but less than expected Oct 09, 2022
Bariatric Surgery in NAFLD Tied to Lower Heart Disease Risk In a large cohort, surgery associated with 49% lower risk of CVD versus nonsurgical care Oct 07, 2022
POEM Trial Results Hold Firm for Long-Term Efficacy in Achalasia Five-year data support peroral endoscopic myotomy, although reflux esophagitis still a problem Oct 06, 2022
Some Environmental Pollutants Linked to IBS PM2.5, airborne toxic releases associated with zip code-level IBS incidence in California Oct 04, 2022
Higher Risk for Treatment Failure With Vedolizumab in Older IBD Patients Particularly for Crohn's disease, according to comparative effectiveness study Sep 30, 2022
No Brain Death? No Problem. New Organ Transplant Protocol Stirs Debate. Is it ethical to pull the plug in patients who aren't brain dead, then restart their hearts? Sep 28, 2022
Have We Been Overcautious With TNF Inhibitors in Pregnancy? Study of IBD patients finds no basis for common practice Sep 26, 2022
FDA Advisors Back Fecal Microbiome Treatment for Recurrent C. Diff Committee members swayed by strong "need" rather than strong data Sep 22, 2022
Noninvasive Gastric Mapping; Best Foods for the Gut? Lab Score for Crohn's News and commentary from the world of gastroenterology and hepatology Sep 22, 2022
Obeticholic Acid Tied to Better Outcomes in Primary Biliary Cholangitis Study comparing randomized trial with two external cohorts showed fewer deaths, transplants Sep 22, 2022
Oral Capsule or Colonic Fecal Transplant for C. Diff: Is One Superior? Real-world data showed no difference in cure rates at 1 and 2 months Sep 20, 2022