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Oncology/Hematology

Leukemia

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Chemo-Free Regimen for Ph+ ALL Yields High Rate of Deep MRD Negativity

Ponatinib-blinatumomab led to durable remissions without transplant in most, but 13% relapsed

9 Hrs Ago
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Pirtobrutinib Delays Progression in CLL Already Treated With a BTK Inhibitor

But no overall survival benefit seen in confirmatory trial

Dec 11, 2024
ASH over a photo of San Diego Convention Center
Year in Review: Chronic Lymphocytic Leukemia

Top news in 2024 included the first CAR-T approval for CLL, triplet regimens, and more

Dec 10, 2024
2024 YEAR IN REVIEW CLL over a computer rendering of CAR T cell therapy in chronic lymphocytic leukemia.
Fixed-Duration Oral Doublet for Fit CLL Wins in Frontline Setting

AMPLIFY trial paves the way for FDA approval of acalabrutinib plus venetoclax

Dec 09, 2024
ASH over a photo of San Diego Convention Center
Promising Results With Epcoritamab Monotherapy in Relapsed/Refractory CLL

Complete responses seen in 43% of patients in expansion cohort of EPCORE CLL-1 study

Dec 08, 2024
ASH over a photo of San Diego Convention Center
Dual Targeted CAR-T Yields 99% Response Rate in Pediatric ALL

Cytokine release syndrome developed in all patients, including grade 3/4 events in nearly half

Dec 07, 2024
ASH over a photo of the San Diego Convention Center
New Standard for Newly Diagnosed Pediatric B-Cell Acute Lymphoblastic Leukemia

Blinatumomab consolidation reduced risk of relapse by 61% versus chemotherapy alone

Dec 07, 2024
ASH over a photo of San Diego Convention Center
Formaldehyde Causes More Cancer Than Any Other Toxic Air Pollutant

Little is being done to curb the risk

Dec 04, 2024
 A photo of a technician putting a human brain into a container of formaldehyde.
Drug Prices Negotiated by Medicare Still Higher Than Other Countries'

All drugs except one remained more expensive in the U.S.

Dec 02, 2024
A photo of a wad of rolled up $100 bills in a prescription medication bottle.
New CAR-T Drug Induces Durable Remissions in ALL, Published Data Show

Results of FELIX study supported obecabtagene autoleucel's recent FDA approval

Nov 27, 2024
Obecabtagene autoleucel (Aucatzyl) over a rendering of CAR-T cells attacking lymphoblastic leukemia cells.
FDA Investigating Blood Cancer Risk With Gene Therapy Skysona

Agency is evaluating the need for further regulatory action

Nov 27, 2024
A photo of a woman holding her boy who suffers from adrenoleukodystrophy.
Advances in TNBC; Mixed News in Lung Cancer Report; Pancreatic Cancer Overdiagnosis?

News, features, and commentary about cancer-related issues

Nov 22, 2024
Onco Break over a computer rendering of a cancer cell.
Sacubitril/Valsartan Curbs Cardiotoxicity From Chemotherapy

Benefit shown in trial of patients flagged for high risk of cardiotoxicity

Nov 20, 2024
AHA over a photo of McCormick Place Convention Center in Chicago, IL.
FDA Approves First Menin Inhibitor for Acute Leukemia

Complete responses in 21% of patients treated with single-agent revumenib

Nov 15, 2024
FDA APPROVED revumenib (Revuforj) over a computer rendering of leukemia cells.
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